In soft gelatin manufacturing, warm liquid gelatin is spread over a slowly revolving, stainless steel drum. A supply of chilled dry air congeals the gelatin as the drum rotates so that a tacky, elastic band rolls off the other end. This thin band is automatically formed into capsules, filled with medicine. If the temperature and humidity are too high, gelatin will start softening and prevent solidification.
From the capsulating machines, the soft, moist capsules are transferred to drying drums or chambers for rapid drying. The moisture then has to be removed gradually to prevent superficial surface hardening. Failing to ensure this will impair the quality of the dried product, making the capsules stick to each other.
Recommendation
The Drying of Soft Gel Capsule is very tricky as it has to be dried in a very controlled condition like RH / Temperature, along with specific air changes and time. The moment any of the conditions deteriorates, the capsule may get brittle, extra soft, etc.
Application |
Temperature |
Humidity
% RH |
°C |
°F |
Soft Gelatine Capsule Drying |
25 |
77 |
20-25 |
Bry-Air Solution
Bry-Air Desiccant dehumidifiers can maintain RH as low as 1% or even lower at constant level, regardless of ambient conditions. These dehumidifiers are CNC fabricated with powder coated finish incorporating high performance Metal Silicate Fluted media, which is bacteria static, non-toxic and thus, ideal to meet GMP requirements of the pharmaceutical industry.